Locostatin M22906
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Specifications
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CAS Number:
133812-16-5
Target:
Raf
Molecular formula:
C14H15NO3
Formula weight:
245,27
Purity:
>98% (HPLC)
Stability:
≥ 2 years
Product description:
Locostatin is a potent and cell permeable inhibitor of Raf kinase inhibitor protein (RKIP)/Raf1 kinase interaction and an inhibitor of cell migration.Locostatin treatment resulted in the activation of the mitogen-activated protein kinase (MAPK) signal pathway (ERK phosphorylation), providing a powerful validation of our targeting protocol.
Note:
Research use only, not for human use.
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