Pyr6 M22852
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Specifications
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CAS Number:
245747-08-4
Target:
TRP/TRPV Channel
Molecular formula:
C17H9F7N4O
Formula weight:
418,27
Purity:
>98% (HPLC)
Stability:
≥ 2 years
Product description:
Pyr6 is a selective TRPC3 inhibitor with IC50 of 0.49 uM(Ca2+ influx inhibition in thapsigargin depleted native RBL-2H3 cells).Pyr6 is an inhibitor of Ca2+ entry, which displays higher potency to inhibit Ca2+ entry mediated by CRAC channel than by TRPC3.Pyr3 is selective inhibitor of TRPC3, inhibited Orai1- and TRPC3-mediated Ca(2+) entry and currents as well as mast cell activation with similar potency.
Note:
Research use only, not for human use.
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