Hoechst 34580 M22850
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Specifications
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CAS Number:
23555-00-2
Target:
Beta Amyloid
Molecular formula:
C27H29N7
Formula weight:
451,57
Purity:
>98% (HPLC)
Stability:
≥ 2 years
Product description:
Hoechst 34580, a cell-permeable fluorescent dye, is used for staining DNA and nuclei.Hoechst 34580 is a good candidate for treating Alzheimer’s disease by inhibiting Aβ formation. 50 μM Aβ42 solutions co-incubated with 100, 25, 12.5, 3.125, 0.78, and 0.1, 0.01 μM Hoechst 34580 at 37 °C for 70 h. Hoechst 34580 can inhibit the aggregation of Aβ42 in a dose-dependent manner.
Note:
Research use only, not for human use.
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