Trilaciclib hydrochloride M22845
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Specifications
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CAS Number:
1977495-97-8
Target:
CDK
Molecular formula:
C24H32Cl2N8O
Formula weight:
519,47
Purity:
>98% (HPLC)
Stability:
≥ 2 years
Product description:
Trilaciclib hydrochloride is an inhibitor of CDK4/6 (IC50s: 1 nM and 4 nM for CDK4 and CDK6).Incubation with Trilaciclib hydrochloride (G1T28) for 24 hours can induce a strong G1 cell cycle arrest (time=0). Cells have re-entered the cell cycle and demonstrate cell-cycle kinetics similar to untreated control cells By 16 hours after Trilaciclib hydrochloride washout.
Note:
Research use only, not for human use.
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