AMG 487 M22838
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Specifications
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CAS Number:
473719-41-4
Target:
CXCR
Molecular formula:
C32H28F3N5O4
Formula weight:
603,59
Purity:
>98% (HPLC)
Stability:
≥ 2 years
Product description:
AMG 487 prevents the chemokines I-IP-10 and I-ITAC from binding to CXCR3. In the cellular assays, AMG 487 inhibits CXCR3-mediated cell migration with IC50 values of 8nM, 15nM and 36nM for I-IP-10, I-ITAC and MIG, respectively.
Note:
Research use only, not for human use.
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