MLN120B M22796
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Specifications
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CAS Number:
783348-36-7
Target:
IκB/IKK
Molecular formula:
C19H15ClN4O2
Formula weight:
366,8
Purity:
>98% (HPLC)
Stability:
≥ 2 years
Product description:
MLN120B is a selective and ATP competitive IKKβ inhibitor (IC50: 60 nM).MLN120B almost completely blocks the stimulation of MM.1S, U266, and INA6 cell growth, as well as IL-6 secretion from BMSCs, induced by multiple myeloma cell adherence to BMSCs [1]. MLN120B shows an inhibitory effect on LPS induced NF-κB activation in RAW267.4 cells.
Note:
Research use only, not for human use.
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