N-Nornuciferine hydrochloride M22767
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Specifications
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CAS Number:
——
Target:
P450
Molecular formula:
——
Formula weight:
——
Purity:
>98% (HPLC)
Stability:
≥ 2 years
Product description:
N-Nornuciferine is an aporphine alkaloid in lotus leaf, significantly inhibits CYP2D6 (IC50: 3.76 μM, Ki: 2.34 μM).N-Nornuciferine strongly inhibits CYP2D6 activity but shows weak or no inhibition of the other four P450 isoenzymes (CYP2C19, CYP3A4, CYP2E1, CYP2C9). N-Nornuciferine competitively inhibits the CYP2D6-catalyzed dextromethorphan O-demethylation (Ki: 2.34 μM).
Note:
Research use only, not for human use.
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