Fz7-21 M22723
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CAS Number:
2247635-23-8
Target:
Wnt/beta-catenin
Molecular formula:
C83H114N18O23S2
Formula weight:
1796,05
Purity:
>98% (HPLC)
Stability:
≥ 2 years
Product description:
Fz7-21 is a peptide antagonist of FZD7 . It antagonises WNT3A-induced Wnt-β-catenin signalling in HEK293 expressing FZD7. Fz7-21 impairs Wnt/β-catenin signaling in HEK293 cells stimulated with exogenous WNT3A (IC50=100 nM) or transfected with a construct expressing WNT3A or WNT1. Fz7-21 also blocks WNT3A-mediated stabilization of β-catenin in mouse L cells (IC50=50 nM).
Note:
Research use only, not for human use.
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