APTO-253 M22678
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Specifications
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CAS Number:
916151-99-0
Target:
c-Myc
Molecular formula:
C22H14FN5
Formula weight:
367.38
Purity:
>98% (HPLC)
Stability:
≥ 2 years
Product description:
APTO-253 inhibits c-Myc expression, stabilizes G-quadruplex DNA, and induces cell cycle arrest and apoptosis in acute myeloid leukemia cells. APTO-253 mediates anticancer activity through the induction of the KLF4 tumor suppressor.APTO-253 (5 μM) induces KLF4 expression and enhances apoptosis induced by NSC 119875 in both SKOV3 and OVCAR3 cells.
Note:
Research use only, not for human use.
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