BMS986260 M22636
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Specifications
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CAS Number:
2001559-19-7
Target:
Other Targets
Molecular formula:
C18H12ClFN6O
Formula weight:
382,07
Purity:
>98% (HPLC)
Stability:
≥ 2 years
Product description:
BMS-986260 is a selective, and orally bioavailable TGFβR1 inhibitor(IC50 = 1.6 nM). BMS-986260 demonstrated functional activity in multiple TGFβ-dependent cellular assays, excellent kinome selectivity, favorable pharmacokinetic properties, and curative in vivo efficacy in combination with anti-PD-1 antibody in murine colorectal cancer (CRC) models.
Note:
Research use only, not for human use.
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