9-ING-41 M22563
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Specifications
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CAS Number:
1034895-42-5
Target:
GSK-3
Molecular formula:
C22H13FN2O5
Formula weight:
404,35
Purity:
>98% (HPLC)
Stability:
≥ 2 years
Product description:
9-ING-41 is a glycogen synthase kinase-3 inhibitor.9-ING-41 (2, 4 μM; 48 hours) decreases neuroblastoma cell viability induces apoptosis[2]. 9-ING-41 (0.1-1 µM) inhibits GSK-3 leading to a decreased expression of the NF-κB target XIAP and significant apoptosis in neuroblastoma cells as shown by PARP cleavage, an apoptosis marker[1]. 9-ING-41 (0.5, 1.0, 1.5, 2.0 μM) inhibits the proliferation rate of all TCL and MCL lines with concentrations as low as 1.0 mM.
Note:
Research use only, not for human use.
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