Jagged-1 188-204 M22523
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Specifications
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CAS Number:
219127-21-6
Target:
Gamma-secretase
Molecular formula:
C93H127N25O26S3
Formula weight:
2107,4
Purity:
>98% (HPLC)
Stability:
≥ 2 years
Product description:
This peptide is a fragment of the JAG-1 protein. JAG-1 is Notch ligand, a peptide that is the most conspicuously expressed ligand in skin. JAG-1 induces epidermal maturation. Exposing submerged keratinocytes monolayers to JAG-1 with elevated calcium concentration produces stratification with loricrin expression and NF-αB activation.
Note:
Research use only, not for human use.
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