7α,25-Dihydroxycholesterol M22488
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Specifications
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CAS Number:
64907-22-8
Target:
Endogenous Metabolite
Molecular formula:
C27H46O3
Formula weight:
418,65
Purity:
>98% (HPLC)
Stability:
≥ 2 years
Product description:
7α, 25-dihydroxycholesterol (7α,25-OHC) is a potent and selective agonist and endogenous ligand of the orphan GPCR receptor EBI2 (GPR183). 7α, 25-dihydroxycholesterol can serve as a chemokine directing migration of B cells, T cells and dendritic cells[1][2], and it is highly potent at activating EBI2 (EC50=140 pM; Kd=450 pM).
Note:
Research use only, not for human use.
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