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Y-33075 dihydrochloride M22457



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Specifications

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CAS Number:

173897-44-4

Target:

ROCK

Molecular formula:

C16H18Cl2N4O

Formula weight:

353,25

Purity:

>98% (HPLC)

Stability:

≥ 2 years

Product description:

Y-33075 dihydrochloride is a selective inhibitor of ROCK(IC50 of 3.6 nM).Y-33075 (Y-39983) is a potent inhibitor of ROCK(IC50 of 3.6 nM). Y-33075 also inhibits PKC and CaMKII more potently than Y-27632(IC50s of Y-27632 and Y-33075 for PKC are 9.0 μM and 0.42 μM, respectively), whereas the IC50s of Y-27632 and Y-33075 for CaMKII are 26 μM and 0.81 μM, respectively.

Note:

Research use only, not for human use.

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