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Exatecan Mesylate M22421



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Specifications

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CAS Number:

169869-90-3

Target:

Topoisomerase

Molecular formula:

C25H26FN3O7S

Formula weight:

531,55

Purity:

>98% (HPLC)

Stability:

≥ 2 years

Product description:

Exatecan Mesylate is a DNA topoisomerase I inhibitor (IC50: 2.2 μM, 0.975 μg/mL).Exatecan Mesylate (DX-8951f) significantly inhibits the proliferation of several cancer cell lines, with mean GI50s of 2.02 ng/mL, 2.92 ng/mL, 1.53 ng/mL, and 0.877 ng/mL for breast cancer cells, colon cancer cells, stomach cancer cells and lung cancer cells, respectively.

Note:

Research use only, not for human use.

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