JH-RE-06 M22367
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Specifications
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CAS Number:
1361227-90-8
Target:
DNA/RNA Synthesis
Molecular formula:
C20H16Cl3N3O4
Formula weight:
468,72
Purity:
>98% (HPLC)
Stability:
≥ 2 years
Product description:
JH-RE-06 disrupts mutagenic translesion synthesis (TLS) by preventing the recruitment of mutagenic POLζ. JH-RE-06 is an effective REV1-REV7 interface inhibitor (IC50=0.78 μM; Kd=0.42 μM), which targets REV1 that interacts with the REV7 subunit of POLζ. JH-RE-06 also improves chemotherapy.
Note:
Research use only, not for human use.
More info:
Email info@sobekbio.com
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