L524-0366 M22217
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Specifications
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CAS Number:
951612-19-4
Target:
Other Targets
Molecular formula:
C13H13ClN4OS
Formula weight:
308,79
Purity:
>98% (HPLC)
Stability:
≥ 2 years
Product description:
L524-0366 is a TWEAK-Fn14 signaling cascade inhibitor.L524-0366 mitigated maladaptive remodeling with TAC. TWEAK induced secretion of the pro-inflammatory chemokine, monocyte chemoattractant protein 1 from WT but not Fn14-/- fibroblasts in vitro, in part through activation of non-canonical NF-κB signaling.
Note:
Research use only, not for human use.
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