HLM006474 M22127
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Specifications
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CAS Number:
353519-63-8
Target:
Other Targets
Molecular formula:
C25H25N3O2
Formula weight:
399,48
Purity:
>98% (HPLC)
Stability:
≥ 2 years
Product description:
HLM006474 is a pan inhibitor of E2F. This inhibits E2F4 DNA-binding (IC50: 29.8 µM in A375 cells).HLM006474 causes the viability of both SCLC and NSCLC lines (IC50 ranging from 15 to 75 µM). HLM006474 displays little activities against E2F4 DNA-binding in A375 cells at 10 and 20 µM, apparently inhibits E2F4 DNA-binding at 40 µM, and increasingly suppresses the effect at 60 and 80 µM concentrations.
Note:
Research use only, not for human use.
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