AV-412 M22121
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Specifications
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CAS Number:
451493-31-5
Target:
EGFR
Molecular formula:
C41H44ClFN6O7S2
Formula weight:
851,41
Purity:
>98% (HPLC)
Stability:
≥ 2 years
Product description:
AV-412 is an EGFR inhibitor (EGFR, EGFR T790M, EGFR L858R, EGFR L858R/T790M and ErbB2 with IC50s of 0.75, 0.79, 0.5, 2.3, 19 nM).In cells, MP-412 inhibited autophosphorylation of EGFR and ErbB2 with IC(50) of 43 and 282 nM, respectively.
Note:
Research use only, not for human use.
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