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LDK378 dihydrochloride M22108



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Specifications

inquiry

CAS Number:

1380575-43-8

Target:

ALK

Molecular formula:

C28H38Cl3N5O3S

Formula weight:

631,06

Purity:

>98% (HPLC)

Stability:

≥ 2 years

Product description:

Ceritinib dihydrochloride is a selective, orally bioavailable and ATP-competitive inhibitor of ALK tyrosine kinase(IC50 of 200 pM), and also inhibits IGF-1R, InsR, and STK22D (IC50 values of 8, 7, and 23 nM, respectively).

Note:

Research use only, not for human use.

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