Pterosin B M14162
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Specifications
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CAS Number:
34175-96-7
Target:
SIK
Molecular formula:
C14H18O2
Formula weight:
218,296
Purity:
>98% (HPLC)
Stability:
≥ 2 years
Product description:
Pterosin B is a potent and specific SIK3 signaling inhibitor that suppresses SIK3 downstream cascades by up-regulating the phosphorylation levels in the SIK3 C-terminal regulatory domain; shows no effect on up-regulation of MEF2 and down-regulation of CRTC2 activities by SIK1 or SIK2; promotes glucose production by up-regulating gluconeogenic gene expression in mouse hepatoma AML-12 cells, decreases the glycogen content and stimulates an association between PHKG2 and SIK3.
Note:
Research use only, not for human use.
More info:
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