NSC 377071 M13794
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Specifications
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CAS Number:
26097-80-3
Target:
Atg
Molecular formula:
C14H14N4O2S
Formula weight:
302,352
Purity:
>98% (HPLC)
Stability:
≥ 2 years
Product description:
NSC 377071 (NSC-377071, NSC377071, Cambendazole) is a novel ATG4B antagonist that inhibits autophagy, with no effect on mTOR and PI3K activities; directly inhibits cellular ATG4B activity induced by starvation or rapamycin and suppresses the lipidation of LC3B and autophagosome formation in response to starvation, suppresses Saos-2 osteosarcoma growth in vivo.
Note:
Research use only, not for human use.
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