Gefitinib-based PROTAC 3 M13575
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Specifications
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CAS Number:
2230821-27-7
Target:
PROTAC
Molecular formula:
C47H57ClFN7O8S
Formula weight:
934,522
Purity:
>98% (HPLC)
Stability:
≥ 2 years
Product description:
Gefitinib-based PROTAC 3 is a VHL-recruiting PROTAC that induces the degradation of EGFR and EGFR mutants with DC50 of 11.7 nM and 22.3 nM for HCC827 cell (Exon 19 del) and H3255 cell (L858R).
Note:
Research use only, not for human use.
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