BAY-1895344 hydrochloride M12910
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Specifications
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CAS Number:
1876467-74-1
Target:
ATM/ATR
Molecular formula:
C20H22ClN7O
Formula weight:
411,894
Purity:
>98% (HPLC)
Stability:
≥ 2 years
Product description:
BAY-1895344 is a potent, selective, orally active ATR inhibitor with low-nanomolar potency; potently inhibits the proliferation of a broad spectrum of human tumor cell lines with mean IC50 of 78 nM; inhibits hydroxyurea-induced H2AX phosphorylation, exhibits strong in vivo anti-tumor efficacy in monotherapy in a variety of xenograft models. Phase 1 Clinical
Note:
Research use only, not for human use.
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