CCT251545 M12536
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Specifications
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CAS Number:
1661839-45-7
Target:
CDK
Molecular formula:
C23H24ClN5O
Formula weight:
421,9225
Purity:
>98% (HPLC)
Stability:
≥ 2 years
Product description:
CCT251545 is a potent, orally bioavailable inhibitor of Wnt signaling with IC50 of 5 nM, also is a potent and selective chemical probe for CDK8 and CDK19 with >100-fold selectivity over 291 other kinases; potently inhibits reporter-based readouts of basal WNT pathway activity in LS174T and SW480 cells in the absence of WNT ligand with IC50 of 23 and 190 nM, respectively.
Note:
Research use only, not for human use.
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