PFM01 M12217
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Specifications
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CAS Number:
1558598-41-6
Target:
DNA Repair Protein
Molecular formula:
C14H15NO2S2
Formula weight:
293,399
Purity:
>98% (HPLC)
Stability:
≥ 2 years
Product description:
PFM01 (SML1735) is a small molecule that specifically inhibits endonuclease, but not exonuclease activity of MRE11, inhibits dsDNA end resection in A549 cells with IC50 of 50-75 uM, blocks the ssDNA-binding path toward the catalytic metal ions and disrupts endonuclease activity.
Note:
Research use only, not for human use.
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