AZD-6738 M11428
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Specifications
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CAS Number:
1352226-88-0
Target:
ATM/ATR
Molecular formula:
C20H24N6O2S
Formula weight:
412,5085
Purity:
>98% (HPLC)
Stability:
≥ 2 years
Product description:
AZD-6738 (AZD6738, Ceralasertib) is a potent and selective inhibitor of ATR with IC50 of 1 nM; shows no significant activity for ATM, DNA-PK and mTOR; inhibits ATR kinase-dependent CHK1 phosphorylation in cells (IC50=74 nM); enhances the therapeutic efficacy of cisplatin in xenograft models; orally active and bioavailable.Gastric Cancer Phase 2 Clinical
Note:
Research use only, not for human use.
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