Acrizanib M10899
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Specifications
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CAS Number:
1229453-99-9
Target:
VEGFR
Molecular formula:
C20H18F3N7O2
Formula weight:
445,406
Purity:
>98% (HPLC)
Stability:
≥ 2 years
Product description:
Acrizanib (LHA510, LHA-510) is a novel potent, selective VEGFR-2 (KDR) inhibitor with IC50 of 17.4 nM in cell-based assays; exhibits <10% remaining kinase activity against only 13 wildtype kinases, CSF1R, Kit, PDGFRα, PDGFRβ, VEGFR1, VEGFR2, VEGFR3, Fms, DDR1, DDR2, TIE1, and ABL1 in a panel of >400 kinases.
Note:
Research use only, not for human use.
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