TCV-309 chloride M10802
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Specifications
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CAS Number:
121494-09-5
Target:
Other Targets
Molecular formula:
C30H34BrClN4O4
Formula weight:
629,9724
Purity:
>98% (HPLC)
Stability:
≥ 2 years
Product description:
A highly potent and selective platelet activating factor (PAF) antagonist; inhibits PAF-induced aggregation of rabbit and human platelets with IC50s of 33 nM and 55 nM respectively; potently protects mice from death induced by PAF and due to anaphylactic shock with ED50 of 2.1 and 2.6 ug/kg (i.v.), respectively; also reverses PAF-induced hypotension and endotoxin-induced hypotension in rats.Coagulation DisorderPhase 2 Discontinued
Note:
Research use only, not for human use.
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