Product overview:

Carrier-free (BSA/glycerol-free) CDX2 mouse monoclonal antibody, clone LBI3G4

Field of research:

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Summary:

The level and beta-cell specificity of insulin gene expression are regulated by a set of nuclear proteins that bind to specific sequences within the promoter of the insulin gene (INS; MIM 176730)and interact with RNA polymerase to activate or repress transcription. The proteins LMX1 (MIM600298) and CDX3 are homeodomain proteins that bind an A/T-rich sequence in the insulin promoter and stimulate its transcription.

Alternative names:

CDX-3; CDX2/AS; CDX3

Species reactivity:

Human, Mouse, Rat

Host:

Mouse

Target:

CDX2

Isotype:

IgG2a

Immunogen:

Recombinant protein expressed in E.coli corresponding to amino acids 1-313 of human CDX2

Clone:

LBI3G4

Conjugation:

Unconjugated

Gene name:

Homo sapiens caudal type homeobox 2 (CDX2), transcript variant 1, mRNA.

Symbol:

CDX2

Pathway:

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Function:

Adult stem cells, Druggable Genome, Embryonic stem cells, ES Cell Differentiation/IPS, Transcription Factors

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

Form:

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Applications & dilution:

WB 1:1000

Storage buffer:

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Storage:

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

Email: info@sobekbio.com

Orders:

Email: orders@sobekbio.com