Product overview:

Carrier-free (BSA/glycerol-free) SDHB mouse monoclonal antibody,clone UMLBI268

Field of research:

Alzheimer's disease, Citrate cycle (TCA cycle), Huntington's disease, Metabolic pathways, Oxidative phosphorylation, Parkinson's disease

Summary:

Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). [UniProtKB/Swiss-Prot Function]

Alternative names:

CWS2; IP; MC2DN4; PGL4; SDH; SDH1; SDH2; SDHIP

Species reactivity:

Human, Mouse, Rat

Host:

Mouse

Target:

SDHB

Isotype:

IgG1

Immunogen:

Full length human recombinant protein of human SDHB (NP_002991) produced in E.coli.

Clone:

UMLBI268

Conjugation:

Unconjugated

Gene name:

Homo sapiens succinate dehydrogenase complex iron sulfur subunit B (SDHB), mRNA; nuclear gene for mitochondrial product.

Symbol:

SDHB

Pathway:

Alzheimer's disease, Citrate cycle (TCA cycle), Huntington's disease, Metabolic pathways, Oxidative phosphorylation, Parkinson's disease

Function:

Druggable Genome

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

Form:

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Applications & dilution:

IHC 1:300

Storage buffer:

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Storage:

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

Email: info@sobekbio.com

Orders:

Email: orders@sobekbio.com