Product overview:

Carrier-free (BSA/glycerol-free) SQSTM1 mouse monoclonal antibody,clone UMLBI12

Field of research:

Request info at info@sobekbio.com

Summary:

This gene encodes a multifunctional protein that binds ubiquitin and regulates activation of the nuclear factor kappa-B (NF-kB) signaling pathway. The protein functions as a scaffolding/adaptor protein in concert with TNF receptor-associated factor 6 to mediate activation of NF-kB in response to upstream signals. Alternatively spliced transcript variants encoding either the same or different isoforms have been identified for this gene. Mutations in this gene result in sporadic and familial Paget disease of bone. [provided by RefSeq]

Alternative names:

A170; OSIL; p60; p62; p62B; PDB3; ZIP3

Species reactivity:

Human, Mouse, Rat

Host:

Mouse

Target:

SQSTM1

Isotype:

IgG2b

Immunogen:

Full length human recombinant protein of human SQSTM1(NP_003891) produced in HEK293T cell.

Clone:

UMLBI12

Conjugation:

Unconjugated

Gene name:

Homo sapiens sequestosome 1 (SQSTM1), transcript variant 1, mRNA.

Symbol:

SQSTM1

Pathway:

Request info at info@sobekbio.com

Function:

Druggable Genome, Transcription Factors

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

Form:

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Applications & dilution:

WB 1:500~2000, IHC 1:150, IF 1:100

Storage buffer:

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Storage:

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

Email: info@sobekbio.com

Orders:

Email: orders@sobekbio.com