Product overview:

Carrier-free (BSA/glycerol-free) Desmin mouse monoclonal antibody, clone LBI6H3

Field of research:

Arrhythmogenic right ventricular cardiomyopathy (ARVC), Dilated cardiomyopathy, Hypertrophic cardiomyopathy (HCM)

Summary:

This gene encodes a muscle-specific class III intermediate filament. Homopolymers of this protein form a stable intracytoplasmic filamentous network connecting myofibrils to each other and to the plasma membrane. Mutations in this gene are associated with desmin-related myopathy, a familial cardiac and skeletal myopathy (CSM), and with distal myopathies. [provided by RefSeq, Jul 2008]

Alternative names:

CDCD3; CSM1; CSM2; LGMD1D; LGMD1E; LGMD2R

Species reactivity:

Human, Mouse, Rat

Host:

Mouse

Target:

DES

Isotype:

IgG2a

Immunogen:

Synthetic peptide (the amino acid sequence is considered to be commercially sensitive) within Human Desmin (NP_001918). The exact sequence is proprietary.

Clone:

LBI6H3

Conjugation:

Unconjugated

Gene name:

Homo sapiens desmin (DES), transcript variant 1, mRNA.

Symbol:

DES

Pathway:

Arrhythmogenic right ventricular cardiomyopathy (ARVC), Dilated cardiomyopathy, Hypertrophic cardiomyopathy (HCM)

Function:

Druggable Genome

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

Form:

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Applications & dilution:

IHC 1:2000

Storage buffer:

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Storage:

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

Email: info@sobekbio.com

Orders:

Email: orders@sobekbio.com