Product overview:

Carrier-free (BSA/glycerol-free) MSLN mouse monoclonal antibody, clone LBI7C2

Field of research:

Request info at info@sobekbio.com

Summary:

This gene encodes a preproprotein that is proteolytically processed to generate two protein products, megakaryocyte potentiating factor and mesothelin. Megakaryocyte potentiating factor functions as a cytokine that can stimulate colony formation of bone marrow megakaryocytes. Mesothelin is a glycosylphosphatidylinositol-anchored cell-surface protein that may function as a cell adhesion protein. This protein is overexpressed in epithelial mesotheliomas, ovarian cancers and in specific squamous cell carcinomas. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed. [provided by RefSeq, Feb 2016]

Alternative names:

MPF; SMRP

Species reactivity:

Human

Host:

Mouse

Target:

MSLN

Isotype:

IgG1

Immunogen:

Full length human recombinant protein of human MSLN (NP_037536) produced in HEK293T cell.

Clone:

LBI7C2

Conjugation:

Unconjugated

Gene name:

Homo sapiens mesothelin (MSLN), transcript variant 2, mRNA.

Symbol:

MSLN

Pathway:

Request info at info@sobekbio.com

Function:

Druggable Genome, Secreted Protein, Transmembrane

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

Form:

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Applications & dilution:

IHC 1:1500

Storage buffer:

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Storage:

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

Email: info@sobekbio.com

Orders:

Email: orders@sobekbio.com