Product overview:

Carrier-free (BSA/glycerol-free) SDC1 mouse monoclonal antibody, clone LBI6A2

Field of research:

Cell adhesion molecules (CAMs), ECM-receptor interaction

Summary:

The protein encoded by this gene is a transmembrane (type I) heparan sulfate proteoglycan and is a member of the syndecan proteoglycan family. The syndecans mediate cell binding, cell signaling, and cytoskeletal organization and syndecan receptors are required for internalization of the HIV-1 tat protein. The syndecan-1 protein functions as an integral membrane protein and participates in cell proliferation, cell migration and cell-matrix interactions via its receptor for extracellular matrix proteins. Altered syndecan-1 expression has been detected in several different tumor types. While several transcript variants may exist for this gene, the full-length natures of only two have been described to date. These two represent the major variants of this gene and encode the same protein. [provided by RefSeq, Jul 2008].

Alternative names:

CD138; SDC; SYND1; syndecan

Species reactivity:

Human

Host:

Mouse

Target:

SDC1

Isotype:

IgG1

Immunogen:

Full length human recombinant protein of human SDC1 (NP_001006947) produced in HEK293T cell.

Clone:

LBI6A2

Conjugation:

Unconjugated

Gene name:

Homo sapiens syndecan 1 (SDC1), transcript variant 1, mRNA.

Symbol:

SDC1

Pathway:

Cell adhesion molecules (CAMs), ECM-receptor interaction

Function:

Druggable Genome, ES Cell Differentiation/IPS, Transmembrane

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

Form:

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Applications & dilution:

WB 1:500-1000

Storage buffer:

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Storage:

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

Email: info@sobekbio.com

Orders:

Email: orders@sobekbio.com