Product overview:

Carrier-free (BSA/glycerol-free) CD276 mouse monoclonal antibody, clone LBI1A10

Field of research:

Cell adhesion molecules (CAMs)

Summary:

The protein encoded by this gene belongs to the immunoglobulin superfamily, and thought to participate in the regulation of T-cell-mediated immune response. Studies show that while the transcript of this gene is ubiquitously expressed in normal tissues and solid tumors, the protein is preferentially expressed only in tumor tissues. Additionally, it was observed that the 3' UTR of this transcript contains a target site for miR29 microRNA, and there is an inverse correlation between the expression of this protein and miR29 levels, suggesting regulation of expression of this gene product by miR29. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011].

Alternative names:

4Ig-B7-H3; B7-H3; B7H3; B7RP-2

Species reactivity:

Human, Mouse, Rat

Host:

Mouse

Target:

CD276

Isotype:

IgG1

Immunogen:

Full length human recombinant protein of human CD276 (NP_079516) produced in HEK293T cell.

Clone:

LBI1A10

Conjugation:

Unconjugated

Gene name:

Homo sapiens CD276 molecule (CD276), transcript variant 2, mRNA.

Symbol:

CD276

Pathway:

Cell adhesion molecules (CAMs)

Function:

Druggable Genome, Transmembrane

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

Form:

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Applications & dilution:

WB 1:500-1000, FLOW 1:100

Storage buffer:

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Storage:

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

Email: info@sobekbio.com

Orders:

Email: orders@sobekbio.com