Product overview:

Carrier-free (BSA/glycerol-free) ERAP1 mouse monoclonal antibody,clone LBI6E3

Field of research:

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Summary:

The protein encoded by this gene is an aminopeptidase involved in trimming HLA class I-binding precursors so that they can be presented on MHC class I molecules. The encoded protein acts as a monomer or as a heterodimer with ERAP2. This protein may also be involved in blood pressure regulation by inactivation of angiotensin II. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Oct 2010]

Alternative names:

A-LAP; ALAP; APPILS; ARTS-1; ARTS1; ERAAP; ERAAP1; PILS-AP; PILSAP

Species reactivity:

Human, Mouse, Rat

Host:

Mouse

Target:

ERAP1

Isotype:

IgG2b

Immunogen:

Human recombinant protein fragment corresponding to amino acids 529-941 of human ERAP1 (NP_001035548) produced in E.coli.

Clone:

LBI6E3

Conjugation:

Unconjugated

Gene name:

Homo sapiens endoplasmic reticulum aminopeptidase 1 (ERAP1), transcript variant 2, mRNA.

Symbol:

ERAP1

Pathway:

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Function:

Druggable Genome, Protease, Secreted Protein

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

Form:

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Applications & dilution:

WB 1:250

Storage buffer:

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Storage:

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

Email: info@sobekbio.com

Orders:

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