Product overview:

Carrier-free (BSA/glycerol-free) GTF2H3 mouse monoclonal antibody,clone LBI6E12

Field of research:

Basal transcription factors, Nucleotide excision repair

Summary:

This gene encodes a member of the TFB4 family. The encoded protein is a subunit of the core-TFIIH basal transcription factor and localizes to the nucleus. The encoded protein is involved in RNA transcription by RNA polymerase II and nucleotide excision repair and associates with the Cdk-activating kinase complex. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 14. [provided by RefSeq, Dec 2012]

Alternative names:

BTF2; P34; TFB4; TFIIH

Species reactivity:

Human, Mouse, Rat

Host:

Mouse

Target:

GTF2H3

Isotype:

IgG1

Immunogen:

Human recombinant protein fragment corresponding to amino acids 1-241 of human GTF2H3 (NP_001507) produced in E.coli.

Clone:

LBI6E12

Conjugation:

Unconjugated

Gene name:

Homo sapiens general transcription factor IIH subunit 3 (GTF2H3), transcript variant 1, mRNA.

Symbol:

GTF2H3

Pathway:

Basal transcription factors, Nucleotide excision repair

Function:

Druggable Genome, Transcription Factors

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

Form:

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Applications & dilution:

WB 1:500

Storage buffer:

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Storage:

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

Email: info@sobekbio.com

Orders:

Email: orders@sobekbio.com