Product overview:

Carrier-free (BSA/glycerol-free) GTF3C4 mouse monoclonal antibody,clone LBI5B4

Field of research:

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Summary:

Essential for RNA polymerase III to make a number of small nuclear and cytoplasmic RNAs, including 5S RNA, tRNA, and adenovirus-associated (VA) RNA of both cellular and viral origin. Has histone acetyltransferase activity (HAT) with unique specificity for free and nucleosomal H3. May cooperate with GTF3C5 in facilitating the recruitment of TFIIIB and RNA polymerase through direct interactions with BRF1, POLR3C and POLR3F. May be localized close to the A box. [UniProtKB/Swiss-Prot Function]

Alternative names:

KAT12; TF3C-delta; TFIII90; TFIIIC90; TFIIIC290; TFIIICDELTA

Species reactivity:

Human, Mouse, Rat

Host:

Mouse

Target:

GTF3C4

Isotype:

IgG1

Immunogen:

Human recombinant protein fragment corresponding to amino acids 583-822 of human GTF3C4 (NP_036336) produced in E.coli.

Clone:

LBI5B4

Conjugation:

Unconjugated

Gene name:

Homo sapiens general transcription factor IIIC subunit 4 (GTF3C4), transcript variant 1, mRNA.

Symbol:

GTF3C4

Pathway:

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Function:

Transcription Factors

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

Form:

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Applications & dilution:

WB 1:500

Storage buffer:

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Storage:

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

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Orders:

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