Product overview:

Carrier-free (BSA/glycerol-free) JUP mouse monoclonal antibody,clone LBI4D5

Field of research:

Acute myeloid leukemia, Arrhythmogenic right ventricular cardiomyopathy (ARVC), Pathways in cancer

Summary:

This gene encodes a major cytoplasmic protein which is the only known constituent common to submembranous plaques of both desmosomes and intermediate junctions. This protein forms distinct complexes with cadherins and desmosomal cadherins and is a member of the catenin family since it contains a distinct repeating amino acid motif called the armadillo repeat. Mutation in this gene has been associated with Naxos disease. Alternative splicing occurs in this gene; however, not all transcripts have been fully described. [provided by RefSeq, Jul 2008]

Alternative names:

CTNNG; DP3; DPIII; PDGB; PG; PKGB

Species reactivity:

Human, Mouse, Rat

Host:

Mouse

Target:

JUP

Isotype:

IgG1

Immunogen:

Human recombinant protein fragment corresponding to amino acids 500-745 of human JUP (NP_002221) produced in E.coli.

Clone:

LBI4D5

Conjugation:

Unconjugated

Gene name:

Homo sapiens junction plakoglobin (JUP), transcript variant 1, mRNA.

Symbol:

JUP

Pathway:

Acute myeloid leukemia, Arrhythmogenic right ventricular cardiomyopathy (ARVC), Pathways in cancer

Function:

Druggable Genome

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

Form:

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Applications & dilution:

WB 1:500, IHC 1:2000

Storage buffer:

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Storage:

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

Email: info@sobekbio.com

Orders:

Email: orders@sobekbio.com