Product overview:

Carrier-free (BSA/glycerol-free) KLRD1 mouse monoclonal antibody,clone LBI8E10

Field of research:

Antigen processing and presentation, Graft-versus-host disease, Natural killer cell mediated cytotoxicity

Summary:

Natural killer (NK) cells are a distinct lineage of lymphocytes that mediate cytotoxic activity and secrete cytokines upon immune stimulation. Several genes of the C-type lectin superfamily, including members of the NKG2 family, are expressed by NK cells and may be involved in the regulation of NK cell function. KLRD1 (CD94) is an antigen preferentially expressed on NK cells and is classified as a type II membrane protein because it has an external C terminus. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Alternative names:

CD94

Species reactivity:

Human

Host:

Mouse

Target:

KLRD1

Isotype:

IgG1

Immunogen:

Human recombinant protein fragment corresponding to amino acids 32-179+Mouse FC of human KLRD1 (NP_002253) produced in HEK293T cell.

Clone:

LBI8E10

Conjugation:

Unconjugated

Gene name:

Homo sapiens killer cell lectin like receptor D1 (KLRD1), transcript variant 1, mRNA.

Symbol:

KLRD1

Pathway:

Antigen processing and presentation, Graft-versus-host disease, Natural killer cell mediated cytotoxicity

Function:

Transmembrane

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

Form:

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Applications & dilution:

FLOW 1:100

Storage buffer:

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Storage:

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

Email: info@sobekbio.com

Orders:

Email: orders@sobekbio.com