Product overview:

Carrier-free (BSA/glycerol-free) UPP2 mouse monoclonal antibody,clone LBI11F11

Field of research:

Drug metabolism - other enzymes, Metabolic pathways, Pyrimidine metabolism

Summary:

Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis. Shows substrate specificity and accept uridine, deoxyuridine, and thymidine as well as the two pyrimidine nucleoside analogs 5-fluorouridine and 5-fluoro-2(')-deoxyuridine as substrates. [UniProtKB/Swiss-Prot Function]

Alternative names:

UDRPASE2; UP2; UPASE2

Species reactivity:

Human, Mouse, Rat

Host:

Mouse

Target:

UPP2

Isotype:

IgG1

Immunogen:

Full length human recombinant protein of human UPP2 (NP_775491) produced in HEK293T cell.

Clone:

LBI11F11

Conjugation:

Unconjugated

Gene name:

Homo sapiens uridine phosphorylase 2 (UPP2), transcript variant 1, mRNA.

Symbol:

UPP2

Pathway:

Drug metabolism - other enzymes, Metabolic pathways, Pyrimidine metabolism

Function:

Request info at info@sobekbio.com

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

Form:

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Applications & dilution:

WB 1:2000

Storage buffer:

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Storage:

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

Email: info@sobekbio.com

Orders:

Email: orders@sobekbio.com