Product overview:

Carrier-free (BSA/glycerol-free) NRGN mouse monoclonal antibody,clone LBI1A2

Field of research:

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Summary:

Neurogranin (NRGN) is the human homolog of the neuron-specific rat RC3/neurogranin gene. This gene encodes a postsynaptic protein kinase substrate that binds calmodulin in the absence of calcium. The NRGN gene contains four exons and three introns. The exons 1 and 2 encode the protein and exons 3 and 4 contain untranslated sequences. It is suggested that the NRGN is a direct target for thyroid hormone in human brain, and that control of expression of this gene could underlay many of the consequences of hypothyroidism on mental states during development as well as in adult subjects. [provided by RefSeq, Jul 2008]

Alternative names:

hng; RC3

Species reactivity:

Human

Host:

Mouse

Target:

NRGN

Isotype:

IgG1

Immunogen:

Human recombinant protein fragment corresponding to amino acids 1-78 of human NRGN (NP_006167) produced in E.coli.

Clone:

LBI1A2

Conjugation:

Unconjugated

Gene name:

Homo sapiens neurogranin (NRGN), transcript variant 1, mRNA.

Symbol:

NRGN

Pathway:

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Function:

Druggable Genome

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

Form:

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Applications & dilution:

WB 1:500

Storage buffer:

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Storage:

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

Email: info@sobekbio.com

Orders:

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