Product overview:

Carrier-free (BSA/glycerol-free) FHIT mouse monoclonal antibody,clone LBI2C2

Field of research:

Non-small cell lung cancer, Purine metabolism, Small cell lung cancer

Summary:

This gene, a member of the histidine triad gene family, encodes a diadenosine 5',5'''-P1,P3-triphosphate hydrolase involved in purine metabolism. The gene encompasses the common fragile site FRA3B on chromosome 3, where carcinogen-induced damage can lead to translocations and aberrant transcripts of this gene. In fact, aberrant transcripts from this gene have been found in about half of all esophageal, stomach, and colon carcinomas. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Oct 2009]

Alternative names:

AP3Aase; FRA3B

Species reactivity:

Human, Mouse, Rat

Host:

Mouse

Target:

FHIT

Isotype:

IgG1

Immunogen:

Full length human recombinant protein of human FHIT (NP_002003) produced in HEK293T cell.

Clone:

LBI2C2

Conjugation:

Unconjugated

Gene name:

Homo sapiens fragile histidine triad diadenosine triphosphatase (FHIT), transcript variant 1, mRNA.

Symbol:

FHIT

Pathway:

Non-small cell lung cancer, Purine metabolism, Small cell lung cancer

Function:

Request info at info@sobekbio.com

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

Form:

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Applications & dilution:

WB 1:500~2000, IHC 1:500

Storage buffer:

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Storage:

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

Email: info@sobekbio.com

Orders:

Email: orders@sobekbio.com