Product overview:

Carrier-free (BSA/glycerol-free) ATG4B mouse monoclonal antibody,clone LBI1A3

Field of research:

Regulation of autophagy

Summary:

Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. Autophagy is postulated to be essential for cell homeostasis and cell remodeling during differentiation, metamorphosis, non-apoptotic cell death, and aging. Reduced levels of autophagy have been described in some malignant tumors, and a role for autophagy in controlling the unregulated cell growth linked to cancer has been proposed. This gene encodes a member of the autophagin protein family. The encoded protein is also designated as a member of the C-54 family of cysteine proteases. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]

Alternative names:

APG4B; AUTL1

Species reactivity:

Human, Mouse, Rat

Host:

Mouse

Target:

ATG4B

Isotype:

IgG2b

Immunogen:

Full length human recombinant protein of human ATG4B (NP_847896) produced in HEK293T Cell.

Clone:

LBI1A3

Conjugation:

Unconjugated

Gene name:

Homo sapiens autophagy related 4B cysteine peptidase (ATG4B), transcript variant 2, mRNA.

Symbol:

ATG4B

Pathway:

Regulation of autophagy

Function:

Protease

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

Form:

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Applications & dilution:

WB 1:500~2000, IHC 1:2000

Storage buffer:

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Storage:

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

Email: info@sobekbio.com

Orders:

Email: orders@sobekbio.com