Product overview:

Carrier-free (BSA/glycerol-free) ALAS2 mouse monoclonal antibody,clone LBI2E4

Field of research:

Glycine, serine and threonine metabolism, Metabolic pathways, Porphyrin and chlorophyll metabolism

Summary:

The product of this gene specifies an erythroid-specific mitochondrially located enzyme. The encoded protein catalyzes the first step in the heme biosynthetic pathway. Defects in this gene cause X-linked pyridoxine-responsive sideroblastic anemia. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]

Alternative names:

ALAS-E; ALASE; ANH1; ASB; SIDBA1; XLDPP; XLEPP; XLSA

Species reactivity:

Human, Mouse, Rat

Host:

Mouse

Target:

ALAS2

Isotype:

IgG1

Immunogen:

Human recombinant protein fragment corresponding to amino acids 139-287 of human ALAS2(NP_000023) produced in E.coli.

Clone:

LBI2E4

Conjugation:

Unconjugated

Gene name:

Homo sapiens 5'-aminolevulinate synthase 2 (ALAS2), transcript variant 1, mRNA; nuclear gene for mitochondrial product.

Symbol:

ALAS2

Pathway:

Glycine, serine and threonine metabolism, Metabolic pathways, Porphyrin and chlorophyll metabolism

Function:

Druggable Genome

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

Form:

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Applications & dilution:

WB 1:2000

Storage buffer:

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Storage:

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

Email: info@sobekbio.com

Orders:

Email: orders@sobekbio.com