Product overview:

Carrier-free (BSA/glycerol-free) IQGAP1 mouse monoclonal antibody,clone LBI7F5

Field of research:

Adherens junction, Regulation of actin cytoskeleton

Summary:

This gene encodes a member of the IQGAP family. The protein contains four IQ domains, one calponin homology domain, one Ras-GAP domain and one WW domain. It interacts with components of the cytoskeleton, with cell adhesion molecules, and with several signaling molecules to regulate cell morphology and motility. Expression of the protein is upregulated by gene amplification in two gastric cancer cell lines. [provided by RefSeq, Jul 2008]

Alternative names:

HUMORFA01; p195; SAR1

Species reactivity:

Human, Mouse, Rat

Host:

Mouse

Target:

IQGAP1

Isotype:

IgG2b

Immunogen:

Human recombinant protein fragment corresponding to amino acids 464-609 of human IQGAP1(NP_003861) produced in E.coli.

Clone:

LBI7F5

Conjugation:

Unconjugated

Gene name:

Homo sapiens IQ motif containing GTPase activating protein 1 (IQGAP1), mRNA.

Symbol:

IQGAP1

Pathway:

Adherens junction, Regulation of actin cytoskeleton

Function:

Druggable Genome

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

Form:

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Applications & dilution:

WB 1:500~2000, IHC 1:5000

Storage buffer:

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Storage:

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

Email: info@sobekbio.com

Orders:

Email: orders@sobekbio.com