Product overview:

Carrier-free (BSA/glycerol-free) GPNMB mouse monoclonal antibody,clone LBI2H7

Field of research:

Request info at info@sobekbio.com

Summary:

The protein encoded by this gene is a type I transmembrane glycoprotein which shows homology to the pMEL17 precursor, a melanocyte-specific protein. GPNMB shows expression in the lowly metastatic human melanoma cell lines and xenografts but does not show expression in the highly metastatic cell lines. GPNMB may be involved in growth delay and reduction of metastatic potential. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Alternative names:

HGFIN; NMB

Species reactivity:

Human

Host:

Mouse

Target:

GPNMB

Isotype:

IgG1

Immunogen:

Human recombinant protein fragment corresponding to amino acids 508-572 of human GPNMB (NP_001005340) produced in E.coli.

Clone:

LBI2H7

Conjugation:

Unconjugated

Gene name:

Homo sapiens glycoprotein nmb (GPNMB), transcript variant 1, mRNA.

Symbol:

GPNMB

Pathway:

Request info at info@sobekbio.com

Function:

Druggable Genome, Transmembrane

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

Form:

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Applications & dilution:

WB 1:500

Storage buffer:

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Storage:

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

Email: info@sobekbio.com

Orders:

Email: orders@sobekbio.com