Product overview:

Carrier-free (BSA/glycerol-free) PAX3 mouse monoclonal antibody, clone LBI4D1

Field of research:

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Summary:

This gene is a member of the paired box (PAX) family of transcription factors. Members of the PAX family typically contain a paired box domain and a paired-type homeodomain. These genes play critical roles during fetal development. Mutations in paired box gene 3 are associated with Waardenburg syndrome, craniofacial-deafness-hand syndrome, and alveolar rhabdomyosarcoma. The translocation t(2;13)(q35;q14), which represents a fusion between PAX3 and the forkhead gene, is a frequent finding in alveolar rhabdomyosarcoma. Alternative splicing results in transcripts encoding isoforms with different C-termini. [provided by RefSeq, Jul 2008]

Alternative names:

CDHS; HUP2; WS1; WS3

Species reactivity:

Human, Mouse, Rat

Host:

Mouse

Target:

PAX3

Isotype:

IgG1

Immunogen:

Full length human recombinant protein of human PAX3(NP_852123) produced in E.coli.

Clone:

LBI4D1

Conjugation:

Unconjugated

Gene name:

Homo sapiens paired box 3 (PAX3), transcript variant PAX3D, mRNA.

Symbol:

PAX3

Pathway:

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Function:

Adult stem cells, Druggable Genome, Embryonic stem cells, ES Cell Differentiation/IPS, Transcription Factors

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

Form:

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Applications & dilution:

WB 1:2000

Storage buffer:

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Storage:

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

Email: info@sobekbio.com

Orders:

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