Product overview:

Carrier-free (BSA/glycerol-free) TRMT12 mouse monoclonal antibody,clone LBI8C7

Field of research:

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Summary:

Wybutosine (yW) is a hypermodified guanosine at the 3-prime position adjacent to the anticodon of phenylalanine tRNA that stabilizes codon-anticodon interactions during decoding on the ribosome. TRMT12 is the human homolog of a yeast gene essential for yW synthesis (Noma and Suzuki, 2006). [supplied by OMIM, Mar 2008]. COMPLETENESS: complete on the 3' end.

Alternative names:

TRM12; TYW2

Species reactivity:

Human

Host:

Mouse

Target:

TRMT12

Isotype:

IgG2a

Immunogen:

Full length human recombinant protein of human TRMT12 (NP_060426) produced in E.coli.

Clone:

LBI8C7

Conjugation:

Unconjugated

Gene name:

Homo sapiens tRNA methyltransferase 12 homolog (TRMT12), mRNA.

Symbol:

TRMT12

Pathway:

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Function:

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Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

Form:

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Applications & dilution:

WB 1:2000

Storage buffer:

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Storage:

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

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Orders:

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